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Prilosec ® OTC (over-the-counter)

Page 1
Omeprazole (chemical name) Pronunciation - o-MEP-ra-zole
Prilosec (brand name)

The Food and Drug Administration (FDA) has approved the 20mg dosage of Prilosec as an over-the-counter medication. Prilosec, a proton pump inhibitor, is currently available in dosages of 10mg, 20mg and 40mgs. Prilosec in the 10mg and 40mg size are prescriptions only. Proton Pump Inhibitors (PPIs) are used for two reasons - chronic heartburn and gastroesophageal reflux disease (GERD), which is a more severe form of heartburn.



Who Should Take Prilosec OTC
Prilosec OTC is for adults 18 years and older with frequent heartburn, when you have heartburn 2 or more days a week. For children under 18 years of age ask a doctor.
  • Prilosec OTC is meant for frequent heartburn, not serious gastroesophageal reflux disease (GERD). See your doctor for GERD. Also, Prilosec OTC is not for people who have heartburn less than one episode a week (or less), or for those who want immediate relief of heartburn.
Directions - How to Take Prilosec OTC
Omeprazole magnesium delayed release tablet 20.6mg (equivalent to 20mg omeprazole) acid reducer. 14 day course of treatment:
  • Swallow 1 table with a glass of water before eating in the morning
  • Take every day for 14 days
  • Do not take more than 1 table a day
  • Do not chew or crush the tablets
  • Do not crush tablets in food
  • Do not use for more than 14 days unless directed by your doctor
It is important not to chew or crush Prilosec OTC tablets, or crush Prilosec OTC tablets in food. This decreases how well Prilosec OTC works.

When To Take Prilosec OTC Again
You may repeat a 14 day course of Prilosec OTC therapy every 4 months.

Page 1 Prilosec OTC
Page 2 Prilosec OTC
Page 3 Prilosec OTC

This summary does not include everything there is to know about the medicine mentioned above. Do not use this medicine without first talking to your doctor. Other brand names or generic forms of this medicine may also be available. Side effects other than those listed above may occur. This medicine may be prescribed for other uses. If you have questions or concerns, or want more information, your doctor or pharmacist has the complete prescribing information about this medicine and possible drug interactions.

Proton Pump Inhibitors
Nexium - Esomeprazole
Aciphex - Rabeprazole
Prevacid - Lansoprazole
Prilosec - Omeprazole
Prilosec OCT
Protonix - Pantoprazole

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