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Barrett's Esophagus

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Barrett's Esophagus and Cancer of the Esophagus

Barrett's esophagus does not cause symptoms itself and is important only because it seems to precede the development of a particular kind of cancer - esophageal adenocarcinoma.

The risk of developing adenocarcinoma is 30 to 125 times higher in people who have Barrett's esophagus than in people who do not. This type of cancer is increasing rapidly in white men. The increase is possibly related to the rise in obesity and * gastroesophageal reflux disease (GERD).

For people who have Barrett's esophagus, the risk of getting cancer of the esophagus is small: less than 1 percent (0.4 percent to 0.5 percent) per year. Esophageal adenocarcinoma is often not curable, partly because the disease is frequently discovered at a late stage and because treatments are not effective.


Normal Esophagus Metaplasia



Definitions For This Page - In Alphabetical Order

* Gastroesophageal Reflux Disease (GERD)
Pronounced - GAH-stroh-eh-SAW-fuh-JEE-ul REE-fluks duh-zeez
Gastroesophageal Reflux Disease (GERD) is the flow of the stomach's contents back up into the esophagus. Happens when the muscle between the esophagus and the stomach (the lower esophageal sphincter) is weak or relaxes when it shouldn't. May cause esophagitis. Also called esophageal reflux or reflux esophagitis. More about GERD.


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References:
digestive.niddk.nih.gov

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