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Barrett's Esophagus

Page 4
Barrett's Esophagus and Cancer of the Esophagus
Barrett's esophagus does not cause symptoms itself and is important only because it seems to precede the development of a particular kind of cancer - esophageal adenocarcinoma. The risk of developing adenocarcinoma is 30 to 125 times higher in people who have Barrett's esophagus than in people who do not. This type of cancer is increasing rapidly in white men. The increase is possibly related to the rise in obesity and gastroesophageal reflux disease (GERD). More about GERD.

For people who have Barrett's esophagus, the risk of getting cancer of the esophagus is small: less than 1 percent (0.4 percent to 0.5 percent) per year. Esophageal adenocarcinoma is often not curable, partly because the disease is frequently discovered at a late stage and because treatments are not effective.



Diagnosis and Screening
Diagnosing Barrett's esophagus is not easy. At the present time, it cannot be diagnosed on the basis of symptoms, physical exam, or blood tests. The only useful test is upper gastrointestinal endoscopy and biopsy. In this procedure, a flexible tube called an endoscope, which has a light and miniature camera, is passed into the esophagus. If the tissue appears suspicious, then biopsies must be done. A biopsy is the removal of a small piece of tissue using a pincher like device passed through the endoscope. A pathologist examines the tissue under a microscope to confirm the diagnosis.

Normal esophagus
Normal esophagus

Metaplasia
Metaplasia


Glossary For This Page
Gastroesophageal Reflux Disease (GERD)
Pronounced - GAH-stroh-eh-SAW-fuh-JEE-ul REE-fluks duh-zeez
Flow of the stomach's contents back up into the esophagus. Happens when the muscle between the esophagus and the stomach (the lower esophageal sphincter) is weak or relaxes when it shouldn't. May cause esophagitis. Also called esophageal reflux or reflux esophagitis.

Page 1 Barrett's Esophagus
Page 2 Barrett's Esophagus
Page 3 Barrett's Esophagus
Page 4 Barrett's Esophagus
Page 5 Barrett's Esophagus
Page 6 Barrett's Esophagus - Conclusion

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