Nexium Dosage

Esomeprazole – chemical name
Pronunciation – ess-oh-MEP-ra-zole
Nexium – brand name

Nexium is available in 20 mg and 40 mg Delayed Release capsules. Recommended adult dosage for treatment of esophagitis is Nexium 20 mg or Nexium 40 mg one capsule daily 4 to 8 weeks (unless otherwise directed by your doctor). If healing is not complete, Nexium can be given for another 4 to 8 weeks. For maintenance of healing, the recommended dosage is Nexium 20 mg once daily. Controlled studies have not extended beyond 6 months.

To treat symptoms of gastroesophageal reflux disease (GERD) in the absence of esophagitis disease, Nexium 20 mg once daily for 4 weeks, is recommended: an additional 4 weeks of treatment may be considered if symptoms persist.

For eradication of helicobacter pylori (H. pylori) to reduce the risk of duodenal ulcer recurrence, 10 days of triple therapy with Nexium (esomeprazole) 40 mg once daily, amoxicillin 1000 mg twice daily and clarithromycin 500 mg twice daily is recommended, (unless otherwise directed by your doctor).

No dosage adjustment is necessary in patients with mild to moderate hepatic impairment. For patients with severe hepatic impairment, the dose of Nexium should not exceed 20 mg. Follow the directions for using Nexium provided by your doctor.


Nexium capsules should be taken by mouth at least one hour before food and at the same time every day, unless otherwise directed by your doctor.

Do not crush or chew the Nexium capsule. SWALLOW THE CAPSULE WHOLE. If you have difficulty swallowing capsules whole, you can empty a Nexium capsule into soft food such as a tablespoon of cool applesauce or yogurt. (The applesauce should not be hot). Do not chew the applesauce or yogurt medication mixture or make up a supply in advance. After taking the drug/applesauce mixture, drink a glass of cool water to ensure complete swallowing of the medicine. The applesauce should be eaten IMMEDIATELY and never stored for later use. The pellets should not be chewed or crushed.

If You Miss A Dose

If you miss a dose of Nexium, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. DO NOT double the dose to catch up. Your doctor will prescribe the dose that is right for you.

Nexium should be stored at room temperature between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container, away from heat, light, and moisture. Do not store Nexium in the bathroom.

If You Take Too Much

If overdose of Nexium is suspected, contact your local poison control center or emergency room immediately. Symptoms of overdose may include confusion, drowsiness, unusual sweating, blurred vision, or unusually fast heartbeat.

Additional Information

If you are taking Nexium for gastric ulcers or gastroesophagea reflux disease, your symptoms should improve within 4 to 8 weeks. An additional 4 weeks of treatment may be considered. If your symptoms do not improve or if they become worse, contact your doctor.

DO NOT SHARE NEXIUM with others for whom it was not prescribed. DO NOT USE Nexium for other health conditions (unless otherwise directed by your doctor) KEEP Nexium and other medications out of the reach of children and pets.

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The information discussed above is a general overview and does not include all the facts, or include everything there is to know about any medicine and/or products mentioned. Do not use any medicine and/or products without first talking to your doctor. Possible side effects of medications, other than those listed, may occur. Other brand names or generic forms of this medicine may also be available. If you have questions or concerns, or want more information, your doctor or pharmacist has the complete prescribing information about this medicine and possible drug interactions.